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Critical-Sized Eardrum Perforation Prevention and Repair

Lai Wen-fu, Taipei Medical University
Year 2016Year Period:2016-08-01 to 2017-08-01

Overview

  • While performing eardrum repair microsurgery, a surgeon needs to work in a relatively deep cavity on small and fragile structures. This mostly one-handed procedure can prove quite a strain detrimental to eyesight.
  • With its core technology for building an absorbable collagen scaffold promoting cellular growth, the team has developed a biomedical material specifically for repairing large-sized tympanic membrane defects. This aerosol therapeutic approach also offers such benefits as faster healing and lower odds of bacterial infection.
  • This solution is also an effective one for addressing excessively small and curved ear canals, surgical complexity, and the difficulty in extending anesthesia time.

Development Process

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Over the course of this project under the Applied Research Incubation Program, the team completed prototype manufacturing, product acceptance criteria, a GMP-compliant manufacturing process, and biocompatibility tests and animal model efficacy tests done in a GLP-certified lab. After Taipeibio Co., Ltd. was established on May 26, 2014, the team continued to offer assistance in product commercialization.

Milestones

2016
  • Admission to the MOST’s Nursery Program.
2015
  • Supported by Thematic Studies on Nano Biomedical Technology to Experience Design Technology.
2014
  • Forms TAIPEIBIO CO., LTD.